Up until last week, there were really only two ways to deal with the dreaded hot flashes and their cousin, the night sweats. A menopausal woman could go on hormones (estrogen or estrogen coupled with progestin) or she could put up and shut up. Neither option was ideal. The first choice wasn’t available to some women, particularly cancer survivors. The second option worked for nobody but was the most common approach for about two millennia or more.
We’re talking about something that is going to be powerful.
On Friday, the Food and Drug Administration (FDA) approved a new drug that should effectively lower the temperature for scores of women.
The drug, fezolinetant, which is to be marketed under the brand name Veozah, is the first to target a neuron in the brain that becomes unbalanced as estrogen levels fall. It would typically be prescribed for women in their 50s during the menopausal phase estimated to last seven years, according to Marci English, a vice president of Astellas Pharma, the maker of the medication.
“I’m so excited about this FDA ruling,” Dr. Mary Rosser, an assistant professor of women’s health at the Columbia University Vagelos College of Physicians and Surgeons and director of Integrated Women’s Health at Columbia, told NBC News. “We’re talking about something that is going to be powerful.”
Read More: Feeling the Pain: The Double Whammy of Hot Flashes and Summer Heat
Here’s the Catch
Hot flashes are the most common issue that menopause brings with it. For some women, the heat is fairly mild. But for others, it’s debilitating. In her book Flash Count Diary, author Darcey Steinke described hot flashes as the feeling of flames that start from her internal organs and radiate toward her skin.
But just try complaining about your heat strokes to anyone—no one really wants to hear about them, especially in the workplace. Actually, ageism is such an issue in so many offices there is a fear that any acknowledgement of why your cheeks are flushing and your shirt is dripping with sweat will identify you as an easy target in the next round of layoffs.
In her book Flash Count Diary, author Darcey Steinke described hot flashes as the feeling of flames that start from her internal organs and radiate toward her skin.
“It’s distracting,” English said. “It’s uncomfortable. It’s something that we kind of managed in silence.”
In yearlong studies, the drug was found to be effective and generally safe, with side effects including stomach pain, diarrhea, and insomnia, according to the FDA. Because signs of liver damage emerged in some patients during study of the drug, the FDA said patients should have blood work conducted before starting the medication to test for existing liver problems and should then repeat the tests during the first nine months of taking the drug.
OK. Here’s the catch. The drug cost is $550 for a 30-day supply, not including rebates. Ouch. A portable, electric fan is a lot cheaper. However, Astellas Pharma, said it would begin a support program “to help patients access the medication they were prescribed.” The Institute for Clinical and Economic Review advised a lower price of $2,000 to $2,600 per year. Still, that’s around $200 a month.
“Unfortunately, the thing that’s going to be the biggest issue I’m sure in my practice and everybody else’s practice is just what the pricing of the drug is,” said Dr. Holly Thacker, director of the Cleveland Clinic Center for Specialized Women’s Health. “It’s very frustrating to have an exciting drug that works, yet most of your patients can’t get access to it or can’t afford it.”
Please, if you’re going to introduce a wonder drug, make sure it’s not a wonder-how-I’ll-pay-for-it drug.
Read More: The Bluetit Swimmers Take the Cold Water Cure for Hot Flashes
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